Biotechnology Cleanrooms
Nicomac designs and builds biotechnology cleanrooms, ensuring sterile, contamination-controlled environments for the safety of research, patients, and end users.

Key Features of Nicomac Biotechnology Cleanrooms
With nearly 50 years of experience in the pharmaceutical cleanroom sector, Nicomac offers cutting-edge solutions tailored to the needs of biotechnological research. Our sterile biotechnology cleanrooms provide contamination-controlled environments ideal for critical processes such as cell and tissue handling, cell and gene therapies, and tissue engineering.
Thanks to our expertise, we provide not only high-quality biotechnology cleanrooms but also comprehensive GMP consulting services, detailed design, site management, specialized installation, and support for plant qualification and validation.
The collaboration with Acotec Mangini Turnkey Division allows us to develop high-containment laboratories, such as BLS3 and BLS4 (PCL3, PCL4), equipped with the most advanced safety systems. The technologies used ensure continuous contamination control through particle and microbiological monitoring systems, providing maximum protection for both operators and samples.


The reliability of a Turnkey project
Nicomac, in synergy with Acotec Mangini Turnkey Division, offers a complete "turnkey" service for the creation of cleanrooms and biotechnology laboratories, including all necessary systems. From design to production, installation, and qualification to validation, we ensure sterile and safe environments, ready for operation in the shortest possible time and compliant with international standards.
Seismic Cleanrooms
The reliability of Nicomac cleanrooms is synonymous with safety, even in the event of seismic activity. In biotechnology laboratories, where operational continuity is critical, we offer the first and only patented Seismic-Proof Cleanroom, developed by Nicomac Mangini. This system, tested according to the international AC156 protocol and compliant with NTC2018 Italian Technical Standards, guarantees unprecedented seismic resistance.
Thanks to the innovative technology developed, we ensure full operational capability of the facilities with zero damage to people and equipment, no restoration costs, and no production downtime even in the event of high-intensity earthquakes.

Modular Building meets Modular Systems
Nicomac Mangini's Modular Pharma solutions represent the future of production facility construction in the pharmaceutical and biotechnology sectors. Through an advanced modular approach, we offer three main solutions: Prefabricated Modular, Container Modular, and MyCUBIK.
The Hybuilt system from Mangini Group allows for the integration of custom modular structural elements with modular interiors, cleanrooms, and other internal partitions, optimizing construction time and costs with a sustainable and highly efficient approach.
Human-Centered Cleanroom
Nicomac Mangini introduces a new design paradigm, placing operator well-being at the heart of cleanrooms. Our approach goes beyond regulatory compliance, aiming to improve the quality of the work environment by reducing stress and enhancing productivity and safety.
In a sector where these aspects are often overlooked, we offer innovative solutions to create less alienating and more comfortable work environments, promoting the psycho-physical well-being of operators and improving overall laboratory performance.

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