# Nicomac Srl

> Nicomac Srl (part of Mangini Group) is an Italian manufacturer of modular cleanrooms and
> pharmaceutical process equipment (coating and granulation). Founded in 1977, operating in
> 65+ countries with over 1,800 completed projects. Headquarters: Liscate (MI), Italy.
> VAT: IT07434210964.

## Company Overview

Nicomac Mangini is a world-leading manufacturer of modular cleanroom systems for controlled
contamination environments. It is the only company in the sector that also designs and
manufactures hi-tech equipment for the pharmaceutical and nutraceutical coating and granulation
process. Nicomac has been part of Mangini Group since October 2023.

Key facts:
- Founded: 1977
- Employees: 153+
- Projects completed: 1,800+
- Countries served: 65+
- Production sites: 4 (Liscate MI, Putignano, Lodi, and USA via Nicos Group)
- Clients include FDA/EMA-approved pharmaceutical manufacturers worldwide

## Products

### Modular Cleanrooms (Camere Bianche)
Complete systems for controlled contamination environments, compliant with ISO 5, ISO 7,
ISO 8 and CNC classifications, and cGMP (Good Manufacturing Practices):
- Modular walls and panels (HPL, glass, metal)
- Suspended ceilings (hermetic, walkable T-Grid, seismic-rated)
- Cleanroom doors (sliding, hinged, roll-up)
- Windows and vision panels (flush-mounted, anti-fogging)
- Lighting systems (recessed, for suspended ceilings)
- Accessories: pass boxes, air showers, HEPA filters, changing rooms

### Coating Equipment (Nicomac Coating System)
- Perforated coating pan (bassina perforata)
- Solid basket coating pan (bassina a cesto solido)
- Confectionery/sugar-coating equipment
- Pellet Powder Layering system
- Easy Coater (compact coating unit)

### Granulation Equipment
- Fluid Bed Dryer (Essiccatore Letto Fluido)
- High Shear Mixer
- Bin Blenders NicoBlender
- Calibrating Mills NicoMill

### Containment
- High-containment isolators (OEB5 certified)

### Turnkey Projects
Full design-build-validate service for cleanrooms and pharmaceutical process plants,
from engineering to commissioning and GMP validation.

## Innovations (Patented / Proprietary)

### Seismic-proof Cleanroom (Cleanroom Antisismica)
The only seismic-certified cleanroom system in the world. Patented by Mangini Group.
Tested on shake table per international protocol AC156 (ICC Evaluation Service).
Fully compliant with Italian NTC2018 construction standards.
Achieves SD0 (Zero Damage State): zero structural damage, zero downtime after earthquake.
Developed in collaboration with Prof. Gennaro Magliulo, University of Naples Federico II,
and CNR. Presented at WCEE 2024 (World Conference on Earthquake Engineering), Milan.
Certifications: AC156, NTC2018 compliant.

### ANIMA® (Artificial Intelligence Nicomac Mangini)
The world's first AI platform integrated into pharmaceutical solid oral dosage (OSD)
manufacturing equipment. Developed by Nicomac Mangini.
Features: real-time process diagnostics, Digital Twin simulation, autonomous pilot mode,
assistant mode, cumulative know-how learning, recipe optimization.
Applications: coating and granulation process control for pharmaceutical and nutraceutical
production. Reduces errors, accelerates new product development, optimizes energy use.

### Human-Centered Cleanroom
A design approach placing operator wellbeing at the center of cleanroom design.
Integrates: biophilic design, natural lighting, ergonomics, space personalization.
Maintains full GMP and ISO compliance while reducing operator stress and improving
productivity and quality of working life.

### Modular Pharma Building
Integration of structural elements, interiors, and systems in a single modular solution
for new pharmaceutical buildings or extensions. Minimal environmental impact,
maximum flexibility, zero downtime during construction.

## Certifications

- **ISO 9001**: Quality management system — Liscate production facility
- **FM Approval**: Fire resistance and material safety certification
- **AC156 Seismic Certification**: International shake-table test protocol (ICC)
- **NTC2018**: Italian national seismic construction standards compliance
- **OEB5**: Maximum containment level for high-potent active ingredients (HPAPI)
- **GMP / cGMP**: Good Manufacturing Practices (EU and international)
- **FDA compliance**: US Food and Drug Administration standards
- **ISO 5 / ISO 7 / ISO 8**: Cleanroom environmental classification (ISO 14644-1)

## Industries Served

- Pharmaceutical (primary sector, including GMP Annex 1 sterile environments)
- Nutraceutical (dietary supplements, OSD production)
- Medical devices
- Biotechnology
- Cosmetics
- Hospital and healthcare
- Therapeutic cannabis
- Industrial cleanrooms (semiconductors, electronics, data centers, gigafactory dryrooms)

## Key URLs

- Homepage: https://nicomac.com
- Cleanrooms: https://nicomac.com/camere-bianche
- Coating & Granulation: https://nicomac.com/coating-e-granulazione
- Seismic Cleanroom: https://nicomac.com/camere-bianche/cleanroom-antisismica
- ANIMA AI: https://nicomac.com/coating-e-granulazione/intelligenza-artificiale-anima
- Human-Centered Cleanroom: https://nicomac.com/camere-bianche/human-centered-cleanroom
- Modular Pharma Building: https://nicomac.com/camere-bianche/modular-building-per-il-pharma
- Turnkey: https://nicomac.com/camere-bianche/turnkey
- Certifications: https://nicomac.com/certificazioni
- About: https://nicomac.com/chi-siamo
- Company History: https://nicomac.com/la-storia
- News: https://nicomac.com/news
- Contact: https://nicomac.com/contatti
- English site: https://nicomac.com/en

## Group Companies (Mangini Group)

- Nicomac Srl — modular cleanrooms and pharma process equipment
- Acotec — turnkey division: https://acotec.it
- Nicos Group (USA) — US operations: https://www.nicosgroup.com
- Mangini Healthcare — healthcare environments
- Mangini Workspace — modular office systems
- Mangini Technical Doors — technical doors
- Mangini Lighting — lighting systems
- Mangini Hospitality — hospitality sector

## Contact

- Website: https://nicomac.com/contatti
- LinkedIn: https://www.linkedin.com/company/nicomac-srl/
- YouTube: https://www.youtube.com/channel/UC0o7BOfYSWh1-DfC2XJyBMA
- PEC (certified email): nicomacsrl@pec.nicomac.it